They run into burning buildings. We fight for their health.
Advancing research, protecting their health, and expanding access to personalized medicine for America's firefighters and first responders.
The threats they can't see
First responders operate in environments defined by repeated toxic exposure6, psychological trauma, sleep disruption7, and intense physical demands, often over the course of entire careers. These risks don't end when the shift does. They accumulate, compounding into elevated rates of cancer6, PTSD, depression, chronic disease, and suicide. Despite well-documented risks, significant gaps remain in research, awareness, and access to therapies that support recovery and long-term health.
“Evidence indicates that the prevalence of posttraumatic stress disorder (PTSD) is substantially higher among first responders than the general population.”
PAHs · Formaldehyde · Benzene · 1,3-Butadiene · Asbestos · Arsenic
The chemistry of the job
Every structure fire is a chemistry problem. When a modern building burns, combustion and pyrolysis produce a complex mixture of volatilized compounds that firefighters inhale and absorb through skin contact across entire careers.
The U.S. firefighter cohort followed by the National Institute for Occupational Safety and Health documents exposure to polycyclic aromatic hydrocarbons, formaldehyde, benzene, 1,3-butadiene, asbestos, and arsenic across routine fireground activity.1 Each of these compounds is independently classified as a known human carcinogen.8 Together, they form an occupational exposure profile that distinguishes the fire service from nearly every other civilian profession.
The body's response to this repeated chemical insult involves oxidative stress, a biological process in which reactive chemicals generated by toxic exposure outpace the body's natural antioxidant defenses. Over years of cumulative exposure, this imbalance is implicated in the elevated cancer, respiratory, and chronic disease outcomes documented in firefighter populations. Supporting the body's endogenous detoxification pathways represents an emerging area of research and clinical interest in occupational health.
PROTECT exists to accelerate that science.
Our four pillars
Advance Research & Evidence
We support partnerships with academic and clinical leaders to expand research into the real health risks firefighters face, from toxic exposure and cancer risk to long-term stress and recovery.
Increase Awareness & Understanding
We share the real experiences of firefighters to raise awareness of occupational risks, reduce stigma, and help more first responders recognize when and how to seek care.
Shape Policy & Systems
We work with policymakers and industry leaders to advance evidence-based solutions that improve prevention, protect firefighter health, and expand access to care at every level.
Expand Access to Care
We help firefighters navigate complex healthcare systems while increasing awareness of clinician-directed treatment options, including personalized and compounded therapies for unmet needs.
Their sacrifice deserves a response.
Join us in advancing the health, resilience, and recovery of those who protect our communities.